Small Intestinal Bacterial Overgrowth (SIBO) often requires a multi-layered approach to restore balance, repair the gut lining, and relieve the symptoms caused by unwanted bacterial activity in the small intestine. While pharmaceutical antibiotics are one option, herbal antimicrobials and natural gut-supporting compounds have been shown in clinical studies to be highly effective, making them a preferred choice for many people looking for a gentler, holistic strategy.

At FixBIOME, we use a coordinated system of ingredients that work together across four key stages of gut repair. Each category targets a different part of the healing process:

1. Repair & Restore Integrity – Strengthening the gut lining, supporting tight junctions, and helping the intestine recover from the damage caused by gas pressure, inflammation, and repeated irritation.

   
   

2. Calm, Soothe & Relieve Symptoms – Easing cramping, bloating, discomfort, spasms, indigestion, and the stress-related symptoms that commonly accompany SIBO.

   
   

3. Rebalance the Microbiome – Using targeted herbal antimicrobials to address bacterial or fungal overgrowth, disrupt biofilms, and rebalance the microbial environment in the small intestine.

   
   

4. Protect & Strengthen for Long-Term Resilience – Supporting immune function, mucosal defence, and long-term microbial stability to reduce relapse risk and maintain a healthy gut environment.

Because SIBO affects people on multiple levels—structural, microbial, and symptomatic—each of these ingredient categories plays a crucial role. When combined, they can restore gut integrity, relieve daily discomfort, address the root cause of overgrowth, and support long-term digestive health.

Below is a breakdown of some of the most clinically studied herbs, extracts, and natural compounds used for SIBO recovery, organised according to their primary function in the gut-healing process.